This book will provide the urologist, oncologist, other clinicians, and more basic science researchers with the latest knowledge of surgical treatment, immunotherapy including immune checkpoints, stereotactic body radiation, minimally invasive treatment and latest developments of translational medicine. This book contains 77 chapters in 5 parts covering debates and difficulty in surgical treatment, precision medicine for individualized therapy, research and perspectives from fresh vision, basic research and translation medicine, molecular genetics, renal tumor immune dysfunction, and signal transduction. An acknowledged expert in that specialty wrote each of the articles, and the list of authors represents decades of experience in dealing with clinical management of RCC.

This book covers topics that over the years have been quite controversial, like lymph node dissection in RCC, nephrectomy in metastatic RCC with venous thrombus, surgical metastasectomy for RCC, acute kidney injury after partial nephrectomy, complex partial nephrectomy, use of anti-vascular and anti-endothelial growth factor targeted agents before cytoreductive surgery, active surveillance and the role of immunotherapy among many other topics.