Since the first version of the Lung Cancer book published in 2015, giant leaps have been attained in all fields, encompassing biological and novel imaging technique disciplines for early lung cancer diagnosis. A large part of this new edition highlights innovative thoracic surgery approaches with outstanding contributions. The Editors-in- Chief, Jianxing He, Thomas A. D’Amico, and Xiuyi Zhi, have succeeded in producing a momentous book that will satisfy the reader’s needs. The book is extensive in all areas of clinical oncology and radiotherapy. It is fair to say that the book marvelously harmonizes all facets of non-small cell lung cancer. The complete final section on modern radiotherapy is well deserved and fulfills all the readers’ expectations to further their learning. This book is not just another book; it will be essential and will surely be found on the desks of physicians, surgeons, biologists, and other scientists and specialists dedicated to the research and care of lung cancer patients.