Pulmonary Nodules and Lung Cancer

Posted On 2018-02-07 02:17:45
Pulmonary Nodules and Lung Cancer
Editors:Yong Song, Erik Folch, Gaetano Rocco, Helmut H. Popper

Publisher: AME Publishing Company; 1st edition (2017)
ISBN-13: 978-9887784173
Hardcover: 317 pages
Language: English
Available at:

Pulmonary nodules are a common diagnostic problem in the daily clinical routine of radiologists, pulmonologists, and oncologists, as well as thoracic surgeons and radiation oncologists. The challenge in the management of pulmonary nodules lies in the necessity to identify the few lung cancers within the vast majority of benign nodules. This diagnostic dilemma is even more pronounced in patients who are undergoing lung cancer screening, which is performed in otherwise healthy heavy smokers with a high risk for lung cancer.

This book provides an in-depth, up-to-date overview of all the different aspects of the management of pulmonary nodules. World-renowned experts in this field have written the chapters in this book. The book focuses on different aspects of lung cancer screening, the management and diagnosis of solid and sub-solid pulmonary nodules, and last, but not least, also on the different treatment strategies of pulmonary nodules.

Honorary Editors

James L. MulshineDepartment of Internal Medicine, Vice President Research, Rush University, 1735 West Harrison Street, Suite 206, Chicago, IL 60612, USA
Helmut ProschDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna 1090, Austria


Yong SongDepartment of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China
Erik FolchDivision of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center and Harvard Medical School, 185 Pilgrim Road, Deaconess 201, Boston, MA 02215, USA
Gaetano RoccoDivision of Thoracic Surgery, Department of Thoracic Surgery and Oncology, Istituto Nazionale Tumori, Fondazione Pascale, IRCCS, Naples, Italy
Helmut H. PopperResearch Unit for Molecular Lung & Pleura Pathology, Institute of Pathology, Medical University of Graz, Graz, Austria

Associate Editors

Tangfeng LvDepartment of Respiratory Medicine, Jinling Hospital, Nanjing 210002, China; Nanjing University Institute of Respiratory Medicine, Nanjing 210002, China
Raymond U. OsarogiagbonThoracic Oncology Research Group, Multidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN, USA
Table of Contents
Lung Cancer Screening
1 Small pulmonary nodules in baseline and incidence screening rounds of low-dose CT lung cancer screening
11 Volume versus diameter assessment of small pulmonary nodules in CT lung cancer screening
21 Lung cancer screening guidelines: common ground and differences
29 Implementing lung cancer screening in the real world: opportunity, challenges and solutions
41 Screening for lung cancer using low-dose computed tomography: concerns about the application in low-risk individuals
53 Implementation of lung cancer screening: promises and hurdles
58 Potential biomarkers for lung cancer screening
Ground-glass Opacity and Lung Cancer
68 What do we know about ground-glass opacity nodules in the lung?
72 Pulmonary ground-glass opacity: computed tomography features, histopathology and molecular pathology
80 Management of ground-glass opacities: should all pulmonary lesions with ground-glass opacity be surgically resected?
90 Computed tomography guided microcoil localization for pulmonary small nodules and ground-glass opacity prior to thoracoscopic resection
Pulmonary Nodules and Lung Cancer
98 The imaging of small pulmonary nodules
104 Risk assessment in relation to the detection of small pulmonary nodules
111 Evaluation of pulmonary nodules in Asian population
119 Comments on characterization of solitary pulmonary nodules with 18F-FDG PET/CT relative activity distribution analysis
124 18F- uorodeoxyglucose positron emission tomography/computed tomography characterization of solitary pulmonary nodules: can we do better?
128 Radiomics of pulmonary nodules and lung cancer
134 From diagnosis to therapy in lung cancer: management of CT detected pulmonary nodules, a summary of the 2015 Chinese-German Lung Cancer Expert Panel
Pulmonary Nodules Diagnosis
146 How to diagnose pulmonary nodules: from screening to therapy
149 Transthoracic needle aspiration in solitary pulmonary nodule
159 18F-FDG-PET/CT in the assessment of pulmonary solitary nodules: comparison of different analysis methods and risk variables in the prediction of malignancy
167 Comparison between endobronchial ultrasound-guided transbronchial biopsy and CT-guided transthoracic lung biopsy for the diagnosis of peripheral lung cancer: a systematic review and meta-analysis
179 Correlation in histological subtypes with high resolution computed tomography signatures of early stage lung adenocarcinoma
188 Lung cancer diagnosis and staging in the minimally invasive age with increasing demands for tissue analysis
200 Early diagnosis of solitary pulmonary nodules
213 Noninvasive computed tomography-guided marking technique for peripheral pulmonary nodules
218 Towards optimal pathologic staging of resectable non-small cell lung cancer
226 Diagnostic and therapeutic value of computed tomography guided coil placement after digital subtraction angiography guided video-assisted thoracoscopic surgery resection for solitary pulmonary nodules
Treatment of Pulmonary Nodules
233 Clinical outcomes of CyberKnife stereotactic radiosurgery for elderly patients with presumed primary stage I lung cancer
241 Sublobar resection for early-stage lung cancer
250 Is surgery still the best management option for early stage NSCLC?
255 Cons: long-term CT-scan follow-up is not the standard of care in patients curatively treated for an early stage non-small cell lung cancer
260 Pros: After stereotactic ablative radiotherapy for a peripheral early-stage non-small cell lung cancer, radiological suspicion of a local recurrence can be suf cient indication to proceed to salvage therapy
264 Image-guided techniques for localizing pulmonary nodules in thoracoscopic surgery
271 Management strategy of solitary pulmonary nodules
278 Preoperative CT-Guided percutaneous wire localization of ground glass pulmonary nodules with a modi ed Kopans wire
283 Post-therapeutic positron emission tomography/computed tomography for early detection of non-small cell lung cancer recurrence
292 Interventional pulmonology approaches in the diagnosis and treatment of early stage non small cell lung cancer
308 Molecular testing in lung cancer in the era of precision medicine

Click the book to view the entire PDF