With the researchers' efforts and their exploration into the mechanisms of rectal cancer, the horizon of scientific knowledge in this field has widened remarkably with dramatic improvements. The management of rectal cancer has witnessed enormous and significant changes since the first recorded surgical resection in 1826. Distinguished experts from 10 countries all around the world are gathered to give their insights into the current and future management of rectal cancer, especially in the section "Treatment overview of Rectal Cancer". This text is comprehensive and fascinating in its consideration for the treatment overview of rectal cancer, including surgical treatment, chemotherapy, radiotherapy, neoadjuvant chemoradiation therapy and immunotherapy in the remaining sections. Drawing on the experience of international leading experts in the field, this book is designed to provide a summary of stateof- the-art developments of rectal cancer treatment and to provide a valuable reference for practicing clinicians in identifying the most appropriate clinical therapy for rectal cancer patients. There is no doubt that current therapies mentioned above will point us in the direction of future improvements.