This book is a collection of papers recently published by experts in this field working in renowned centers all over the world, which provides a comprehensive review of the use of this technology in the treatment of thoracic surgical diseases, covering three main areas: consensus, anesthesia support, and current status of applications. In this way, readers gain a complete scenario of the current state of tubeless VATS, and this textbook will undoubtedly represent a valuable resource not only to thoracic surgeons but also to anesthesiologists and all allied healthcare professionals. Moreover, senior surgeons may also have an excellent opportunity to go deep into tubeless VATS, profitably comparing their clinical practice with the reported experiences of the most relevant experts in this field. Of particular importance, this is the era of Precise Medicine and ERAS; therefore, we should sometimes consider the tubeless VATS.